Caffeine, a central nervous system stimulant used in Thermonex EF as an aid to stay awake, for mental alertness due to fatigue or, in combination with other ingredients for pain relief, and as a power and energy accelerate. Caffeine is available alone as a non-prescription drug over the counter medication, in combination with other non-prescription drugs, and in prescription drug combinations for relief of pain and headache. Like Ephedra, caffeine acts to increase mental alertness while providing additional energy for weight loss and exercise training. Caffeine is more than a stimulant as it goes deep into muscles to provide long lasting power while delaying the onset of muscle fatigue. Also great before working out, caffeine fights fatigue and helps you get ready for your workout. For dieters feeling sluggish that need just a little something extra to get them through the day, caffeine is the obvious no-calorie stimulant solution. Many products containing caffeine anhydrous contain as much caffeine as one or two cups of coffee. It is recommended to limit the use of caffeine containing medications, foods, or beverages while taking caffeine supplements as excess caffeine intake may cause nervousness, irritability, sleeplessness and occasional rapid heart beat.

Diiodotyrosine, also known as DIT, is a drug used to treat hyperthyroidism and is often included in dietary supplements designed to increase the metabolism and burn fat. It is considered a synthetic anti-thyroid agent that is used to decrease the amount of hormones the thyroid produces. In some cases it produces a response more quickly than radioactive iodine therapy while not causing the thyroid gland permanent damage. Possible serious side effects of this drug are the suppression of bone marrow which can lead the patient to having a decreased number of blood leucocytes, bronchitis, hepatitis, jaundice, skin rashes, and/or syndromes that are similar to systemic lupus erythematosus.

Evodiamine has been used in Chinese medicine and by Chinese herbalists for centuries for weight loss purposes. It is an extract from a plant, Evodia or Tetradium, actually a tree genus of the family Rutaceae. The bee bee tree, as it is called besides Euodia and Evodia, provide a bioactive alkaloid that the Chinese have nicknamed Wu-Chu-Yu. This extract not only can interact with UCP1, a thermogenic protein, which as a consequence burns energy as heat, but also has shown in studies on mice to reduce the fat uptake. Evodiamine seems to increase the resting temperature of humans, whereby increased fat and calories are burned in order to supply the heat. Deemed a breakthrough in thermogenesis, evodiamine is subject of several clinical studies.

Green Tea Extract is very popular with the health conscious community, mainly because of the broad antioxidant features, which are provided by the green tea catechins. It is a very popular nutritional supplement, much more popular than regular green tea, because several green tea extract products have no caffeine. Caffeine is actually contained in larger quantities in green tea than in coffee. Besides the already mentioned catechins, further polyphenols are included in the Asian tea favorite. Green tea furthermore contains carotenoids, ascorbic acid – more commonly known as Vitamin C, Minerals and tocopherols. While there are many proven qualities of green tea extracts, some lesser researched effects have been observed, like reduction of LDL cholesterol, increasing the levels of norepinephrine, weight loss and additional antioxidant qualities.

Iodotyrosone, which is a form of tyrosine with iodine added.

L-Tyrosine is an amino acid that may be found in foods such as meats, dairy products, wheat, fish, and oats. It plays an important role in the production of neurotransmitters such as L-dopa, dopamine, norepinephrine, and epinephrine that aids in the proper functioning of the brain. It prevents feelings of anxiety, irritability, frustration, sadness and depression. It also helps in losing weight because it aids in suppressing appetite and cravings. It also has the ability to enhance the libido. L-Tyrosine also protects the skin from UV light rays by being converted into melanin. It also benefits people with Alzheimer’s disease and dementia.

Naringin, which is a citrus flavanoid that is found in grapefruit. Naringin is commonly used in energy supplements as it may extend the duration of the effects of caffeine.

Octopamine is a biogenic substance which is containing an amine group, apparently related to noradrenaline, which is a catecholamine functioning as both, neurotransmitter and a hormone. Similar to norepinephrine, which is another name for noradrenaline, octopamine may act as a stress hormone, triggering increased heart rate, energy consumption and blood flow, even the blood pressure. One side effect of octopamine is apparently the release of fat from the adipocytes, which are the fat cells where excess energy is being stored. This side effect prompted the use of octopamine as a dietary supplement aimed at weight loss, but used in combination with other stimulants. Octopamine has been discovered in the middle of the twentieth century, but the use as a fat removal agent is very recent.

Synephrine is an adrenergic amines and stimulant with beta-3 receptors. It functions to increase metabolic rate with no effect to heart rate or blood pressure. Synephrine releases adrenaline and noradrenalin in the adipose tissue and the liver. Stimulation of the beta-3 receptor sites to educe the breakdown of fat. It can be added to the group of stimulants, to which belong such supplements as caffeine or ephedrine. Can be used to boost energy, suppress appetite and enhance metabolic rate to burn more calories and increased the energy, but it does not cause so undesired negative cardiovascular effects. Its active ingredients include gelatin, cellulose, and silica and magnesium strearate. Its weight loss abilities are associated with citrus aurantium (synephrine) supplements which give it the stimulant like effects of the alkaloids.

Yerba Matte Pronounced, YARE-ba MAH-tay, yerba mate is a shrub that belongs to the holly family. A Key Element in Thermonex EF Yerba mate contains the following vitamins, minerals and additional compounds: Vitamin A to Vitamin C Vitamin E Vitamin B1 Vitamin B2 Vitamin Niacin Vitamin B5 Vitamin B complex Minerals: Calcium Iron Manganese Magnesium Potassium Phosphorus Selenium Additional Compunds: Flavonols Polyphenols Antioxidants Pantothenic Acid and more The leaves of yerba mate have been found to offer strength while the stems inspire energy.