Caffeine is a methylated xenthine discovered in 1819 by Friedrich Ferdinand Runge, a German chemist. Sources of Caffeine include beans, fruit and leaves of some plants. Caffeine available for human consumption is most commonly extracted from the coffee plant cherries and tea bush leaves, as well as foods and drinks that contain products derived from the kola nut. Caffeine can temporarily reduce the sensation of being tired; however, this does not mean that it eliminates the need for sleep. Generally, twenty five to fifty milligrams of caffeine is enough for most consumers to report an increase in alertness and arousal. Caffeine should be not be consumed by those with fecal incontinence as it relaxes the internal anal sphincter muscles.

Diiodotyrosine, used by the thyroid hormones T4 and T3, Diiodotyrosine may help the thyroid gland to maintain proper function and help preserve lean muscle and supports the thyroid without suppressing TSH levels.

Evodiamine is a chemical that is extracted from a particular species of plants that has been shown to reduce overall fat intake.

Green Tea Extract is of immense use to treat body ache, headaches and poor digestion. The green tea extract contains polyphenols to high levels and is an opulent source of antioxidant. It has the power of fighting free radicals more than vitamin E. the polyphenols present in green tea extract protect against respiratory and digestive infections. It blocks the carcinogens actions that promotes cancer and reduces the cholesterol levels. Green tea extract helps in metabolizing fat. The dieters can feel the weight loss without side effects and jitters. The green tea extract decreases the heart disease risk and also helps in preventing liver failure. The benefits of green tea extract are many, but as it contains caffeine, medical experts should be consulted prior to using it. Green tea extract also defends dental plaque. Green tea extracts prevents even liver transplant failure, but pregnant women should take green tea only after doctor consultation.

Iodotyrosone, which is a form of tyrosine with iodine added.

L-Tyrosine is a proteinogenic polar amino acid, deemed not essential because it can be synthesized by the human body. As a member of the amino acid group that is being used by cells to build proteins, this building block derived its name from the Greek word tyros, which means cheese, because it was discovered in the cheese protein casein. L-Tyrosine can be synthesized from phenylalanine and can be found in foods high on protein, like soy products, poultry, cheese, bananas, dairy products and several seeds, including the sesame seeds. The unique phenol functionality and the occurrence in proteins that belong to the signal transduction process, make this amino acid different. Tyrosine can be converted by tyrosine hydroxylase enzyme into levodopa, a psychoactive drug that is used, among other uses, for clinical treatment of Parkinson’s disease. It is also involved in the synthesis of dopamine, norepinephrine and epinephrine.

Naringin is the major flavonoid glycoside in grapefruit and gives grapefruit juice its bitter taste. It occurs naturally in all citrus fruits so it is also called citrus Naringin. It is used in medicine for its pharmacological effects such as an antioxidant and for blood lipid lowering. Research also shows that Naringin can be used for inhibition of selected drug-metabolizing cytochrome P450 enzymes, including CYP3A4 and CYP1A2. Its anti-cancer effects are also being studied by researchers. Naringin is treated with potassium hydroxide or another strong base, and then catalytically hydrogenated to make naringin dihydrochalcone, which is used as a sugar-free sweetener 300 times sweater then sugar.

Octopamine, which is a trace amine, recently believed to be a lipotropic for fat loss. Octopamine has low oral bioavailability and is readily broken down by MAOI, as well as metabolized by the gut wall, which may mean it would not work well when taken orally, but more research is needed to prove its positive or negative effects.

Synephrine is an ingredient that is obtained mainly from the fruit of a small citrus tree, the Citrus aurantium, also known as bitter orange, zhi shi and sour orange. Synephrine is viewed as the safer version of ephedrine, whereby the properties include weight loss, increased fat burning, raised metabolism, as well as boosted energy levels. With such properties, this drug became instantly popular with the weight loss and control circles, but also with the body building community, and is now used in Thermonex EF where fat burning and higher energy level properties are eagerly sought after. Initial research show stimulation of beta-3 receptors, whereby no increased heart rate or blood pressure was observed. It seems that synephrine induces lipolysis and stimulates similarly to caffeine. Some have also observed that synephrine suppresses appetite and increases the metabolic rate.

Yerba Matte is believed to possess cancer-fighting properties and has shown to have a relaxing effect on muscle tissues and a stimulating effect on heart tissues.