Caffeine, a central nervous system stimulant used in Thermonex EF as an aid to stay awake, for mental alertness due to fatigue or, in combination with other ingredients for pain relief, and as a power and energy accelerate. Caffeine is available alone as a non-prescription drug over the counter medication, in combination with other non-prescription drugs, and in prescription drug combinations for relief of pain and headache. Like Ephedra, caffeine acts to increase mental alertness while providing additional energy for weight loss and exercise training. Caffeine is more than a stimulant as it goes deep into muscles to provide long lasting power while delaying the onset of muscle fatigue. Also great before working out, caffeine fights fatigue and helps you get ready for your workout. For dieters feeling sluggish that need just a little something extra to get them through the day, caffeine is the obvious no-calorie stimulant solution. Many products containing caffeine anhydrous contain as much caffeine as one or two cups of coffee. It is recommended to limit the use of caffeine containing medications, foods, or beverages while taking caffeine supplements as excess caffeine intake may cause nervousness, irritability, sleeplessness and occasional rapid heart beat.

Diiodotyrosine, also known as DIT, is a drug used to treat hyperthyroidism and is often included in dietary supplements designed to increase the metabolism and burn fat. It is considered a synthetic anti-thyroid agent that is used to decrease the amount of hormones the thyroid produces. In some cases it produces a response more quickly than radioactive iodine therapy while not causing the thyroid gland permanent damage. Possible serious side effects of this drug are the suppression of bone marrow which can lead the patient to having a decreased number of blood leucocytes, bronchitis, hepatitis, jaundice, skin rashes, and/or syndromes that are similar to systemic lupus erythematosus.

Evodiamine, a bioactive alkaloid extract from the Evodiae Fructus plant, sometimes called Wu-Chu-Yu. Evodiamine is related to capsaicin, found in cayenne pepper. Evodiamine is a vanilloid receptor agonist, and may enhance lipolytic activity. Evodiamine has been shown to raise the body’s skin temperature and decrease core temperature, which is thought to burn calories and fat for energy.

Green Tea Extract is very popular with the health conscious community, mainly because of the broad antioxidant features, which are provided by the green tea catechins. It is a very popular nutritional supplement, much more popular than regular green tea, because several green tea extract products have no caffeine. Caffeine is actually contained in larger quantities in green tea than in coffee. Besides the already mentioned catechins, further polyphenols are included in the Asian tea favorite. Green tea furthermore contains carotenoids, ascorbic acid – more commonly known as Vitamin C, Minerals and tocopherols. While there are many proven qualities of green tea extracts, some lesser researched effects have been observed, like reduction of LDL cholesterol, increasing the levels of norepinephrine, weight loss and additional antioxidant qualities.

Iodotyrosone, which is a form of tyrosine with iodine added.

L-Tyrosine is an amino acid that may be found in foods such as meats, dairy products, wheat, fish, and oats. It plays an important role in the production of neurotransmitters such as L-dopa, dopamine, norepinephrine, and epinephrine that aids in the proper functioning of the brain. It prevents feelings of anxiety, irritability, frustration, sadness and depression. It also helps in losing weight because it aids in suppressing appetite and cravings. It also has the ability to enhance the libido. L-Tyrosine also protects the skin from UV light rays by being converted into melanin. It also benefits people with Alzheimer’s disease and dementia.

Naringin, which is a citrus flavanoid that is found in grapefruit. Naringin is commonly used in energy supplements as it may extend the duration of the effects of caffeine.

Octopamine is a biogenic substance which is containing an amine group, apparently related to noradrenaline, which is a catecholamine functioning as both, neurotransmitter and a hormone. Similar to norepinephrine, which is another name for noradrenaline, octopamine may act as a stress hormone, triggering increased heart rate, energy consumption and blood flow, even the blood pressure. One side effect of octopamine is apparently the release of fat from the adipocytes, which are the fat cells where excess energy is being stored. This side effect prompted the use of octopamine as a dietary supplement aimed at weight loss, but used in combination with other stimulants. Octopamine has been discovered in the middle of the twentieth century, but the use as a fat removal agent is very recent.

Synephrine or oxedrine is a drug derived from bitter orange or Citrus aurantium. It is an aromatic compound with the systematic name 4-[1-hydroxy-2-(methylamino)ethyl]phenol which indicates that it has an attached hydroxyl group at para position and a methyl amino group at another position. It is not one of those compounds on which an extensive scientific study has been done. However, it has some positional isomers such as the neosynephrine as well as other compounds. Studies indicate that it could act as a Beta-3 adrenergic receptor which means that if taken as a supplement it enhances the breakdown of fat to release energy and also increases heat production in the muscles.

Yerba Matte has a level of caffeine and is therefore a stimulant aids in toning, balancing and strengthening the body, aids in digestion, calms and balances nerves and is also used to help treat allergies and sinusitis.