Advanta Z- Made from bitter orange or the extract of citrus aurantium, Advantra Z was used in China for treating chest and stomach ailments. After the FDA banned ephedra, research was being done to find a better replacement for an effective weight loss supplement, this is why it is used in Thermo Fire . The research gave birth to Advantra Z, which soon became one of the main ingredients in dietary supplements used for weight loss. As such, there is no evidence of side effects caused due to consumption of Advantra Z. Today, it has become extremely popular as a premier weight loss supplement due to its fat burning (thermogenesis) ability. Simply put, it alters the body's way of metabolizing fat leading to considerable weight loss. Despite its ability to induce weight loss, different people respond differently to this supplement. Every body being unique, what fits for one may not be suitable for someone else.

Bacopa Monnieri, also known as Brahmi, coastal waterhyssop and thyme leafed gratiola is a creeping herb that is often found in wetlands and near muddy shores. This flowering perennial is at home mostly in marshy regions of Asia, whereby India, China, Sri Lanka and Nepal are most notable. Ayurveda, the traditional medicine system of India and currently very popular branch of alternative medicine all over the world has this herb listed as possible treatment for epilepsy and also asthma. Recent studies have concluded that the Bacopa monnieri seems to have nootropic effects, enhancing cognitive abilities. Further properties include anti-anxiety and antioxidant properties. Another study has verified that Bacopa monnieri seems to improve intellectual activity, and ingredients sulfhydryl and polyphenol seem to have possibilities in treatments of Alzheimer’s patients.

Bioperine, a standardized extract from the fruit of Piper nigrum L (black pepper) or Piper longum L (long pepper). It contains 95 percent of piperine. Bioperine is used in conjunction with other herbs or vitamins to increase their absorption and digestion to make them more effective.

Caffeine is the most widely available legal psychoactive stimulant drug. Also known as theine, methyltheobromine and trimethylxanthine, this xanthine alkaloid is not only found in coffee beans, but also in guaranine that is derived from guarana, mateine derived from mate, theine which is found in various teas and the kola nut, which is the base flavor of various Cola soft drinks. It stimulates the central nervous system, where it restores alertness and wards off drowsiness. Caffeine is also know to display certain diuretic properties, is an ergogenic, an atagonist of the adenosine receptors, and a cAMP levels increasing factor. It seems that caffeine helps prevent the onset of Parkinson’s disease and in the long run lowers the possibility of developing a heart disease.

Cellulose is the structural component of the primary cell wall of green plants, many forms of algae and the oomycetes. Cellulose is not digestible by humans and is often referred to as 'dietary fiber' or 'roughage', acting as a hydrophilic bulking agent for feces.

Epigallocatechin Gallate (EGCG) is among the major catechins found in green tea. It belongs to the class flavan 3 ol of flavonoids, and is polyphenolic matter. Black tea also contains EGCG but in lower quantities. Epigallocatechin gallate makes up about 30% of dry weight of the green tea leaves. EGCG is the most powerful antioxidant present in green tea. It helps to burn fat, increase metabolism, and lower the storage of fat. Researches show that EGCG can be beneficial in curing many types of cancers, like bladder, cervical, prostate, and brain cancer. It also builds up the immune system and protects the body from many diseases.

Evodia Rutaecarpa contains the extracts of the plant Tetradium, which is a genus in the family Rutaceae, also known as the Bee bee tree, or Evodia. This extracts contain a chemical which is called evodiamine, which seems to influence the uncoupling protein 1, also called thermogenin, which is involved in the process allowing energy to be burned as heat. Evodiamine is actually a bioactive alkaloid, used by the traditional Chinese medicine for ages under the name Wu Chu Yu in connection with weight control and fat burning solutions for overweight to obese people. Evodiamine seems to interact with vanilloids, with the effect that the uptake of fat is lowered, but at the same time the fat burning rate is increased, resulting in actual weight loss.

Evodiamine has been used in Chinese medicine and by Chinese herbalists for centuries for weight loss purposes. It is an extract from a plant, Evodia or Tetradium, actually a tree genus of the family Rutaceae. The bee bee tree, as it is called besides Euodia and Evodia, provide a bioactive alkaloid that the Chinese have nicknamed Wu-Chu-Yu. This extract not only can interact with UCP1, a thermogenic protein, which as a consequence burns energy as heat, but also has shown in studies on mice to reduce the fat uptake. Evodiamine seems to increase the resting temperature of humans, whereby increased fat and calories are burned in order to supply the heat. Deemed a breakthrough in thermogenesis, evodiamine is subject of several clinical studies.

Gelatin constitutes the shells of pharmaceutical capsules in order to make them easier to swallow. Gelatin is a translucent, colourless, brittle, nearly tasteless solid substance, extracted from the collagen inside animals' connective tissue. It has been commonly used as a gelling agent in food, pharmaceutical, photography, and cosmetic manufacturing.

Green Tea Extract is a widely consumed beverage in the world. It is well known for its antioxidant properties. It is traditionally used to treat ailments such as headaches, poor digestion, and body aches. Green tea extract is rich in catechin which increases the level of cholecystokinin that suppresses that appetite, thus promoting weight loss. It also contains Pheophytins, chlorophylls, caffeine, and carotenoids that have anti-genotoxic and antioxidant properties. It also helps in thermogenesis and in the metabolism of fat, promoting weight loss. The EGCG content protects the body from free radical damages. It also blocks the carcinogens that may cause cancer and protects the body from digestive and respiratory infections. It also has anti-bacterial properties.

Guarana contains a significant amount of guaranine, a substance that is similar to caffeine found in coffee beans. It helps stimulate the adrenal glands and increase the production and release of hormones such as epinephrine, norepinephrine (adrenaline), and dopamine. This helps the metabolism of the body that enhances fat loss, and increases energy and endurance. It helps the body burn the fats to be used for energy. It aids in fighting stress, weakness and fatigue. As a stimulant, it also improves mental alertness, clarity, focus, concentration, and memory retention. Guarana also also improves the libido or sex drive in both men and women. Guarana also contains tannins that help prevent diarrhea and soothes the digestive system.

L-Pyroglutamic acid is a type of an amino acid found in the body. It boosts brain functions without causing harmful side effects. It promotes the production of Acetylcholine which is an important chemical that helps the brain cells communicate with each other. Acetylcholine improves memory retention – both old information and new information. L-Pyroglutamic acid protects the brain from chemicals that could potentially worsen the memory. L-Pyroglutamic acid can also prevent Alzheimer’s disease. It improves the blood circulation in the brain, enhancing the metabolic processes to take place in the brain cell. It enables the brain to use an increase amount of glucose that gives the brain cells more energy, thus, improving the mood.

L-Tyrosine is an amino acid that is nonessential. It is synthesized from the body from phenylalanine which is also an amino acid. L-Tyrosine has the power to have an effect on the neurotransmitters and this affects various health conditions including depression, mood disorders and Parkinson’s disease. Many such studies have proved that L-Tyrosine helps people having depression. It acts as a precursor and eases the effects of psychosocial, environmental and physical stress. L-Tyrosine turns into melanin by the skin cells and the dark pigment prevents the ultraviolet light from affecting. The thyroid hormones playing a significant role in the process of the body also contain tyrosine. L-Tyrosine is commonly found in all the dairy products, fish, oats, wheat, meat and also in all other protein containing foods. This is also found to be beneficial for people trying to withdraw alcohol. L-Tyrosine has not exhibited severe side effects, yet taking it should be recommended by doctors.

Magnesium Stearate is coommonly used as a filling agent in the manufacture of capsules and tablets, such as vitamins, the source of this ingredient is typically bovine. However, there is an increasing number of vegetarian options in which the product specifically indicates it contains magnesium stearate from vegetable sources.

Maltodextrins are polysaccharides used as food additives. Their general formula is C6nH(10n+2)O(5n+1). Their Mol.mass is variable according to length of glucose chain. Maltodextrins are classified by DE (dextrose equivalent) between 3 and 20 (the longer the glucose chain, lower the DE number). 5 DE Maltodextrin is a low DE Maltodextrin. It is commonly derived from starch enzymaticlly. It has viscosity and it gives texture, body and moisture control in foods. 5 DE Maltodextrin has a slightly sweet taste which is much less sweeter than sucrose. This property is attributable to the fact that it has higher amounts of glucose bound in chains rather than being free. When consumed by athletes, it provides time release glucose to the blood and provides energy over a long time.

Niacin, also called Vitamin B3, is a water-soluble vitamin needed for the conversion of food into energy so that it may be used by the body. Niacin also helps metabolize protein, sugar and fat.

Raspberry Ketones- Red raspberries contain a phenolic compound, which is the main aroma in red raspberries. This raspberry ketone is being used in cosmetics and perfume industries, but also as a food additive. While the use as a weight loss agent has not yet been clinically tested on human subjects, preliminary research in lab mice has shown that raspberry ketones in high doses show a norepinephrine induced lipolysis. This leads to the effect that even a diet high on fats did not result in higher body weight. This fact has immediately led to the embrace of raspberry ketones by the weight loss and body building communities, despite the fact that raspberry fruits would be much healthier, containing ellagic acid, catechins, salicylic acid, and various other polyphenols, besides large quantities of Vitamin C.

Silica is silicon dioxide, a trace mineral found in bones, teeth, skin, eyes, glands and organs. It also helps keep skin elastic. Silica works with calcium to maintain bone strength.

Synephrine is an ingredient that is obtained mainly from the fruit of a small citrus tree, the Citrus aurantium, also known as bitter orange, zhi shi and sour orange. Synephrine is viewed as the safer version of ephedrine, whereby the properties include weight loss, increased fat burning, raised metabolism, as well as boosted energy levels. With such properties, this drug became instantly popular with the weight loss and control circles, but also with the body building community, and is now used in Thermo Fire where fat burning and higher energy level properties are eagerly sought after. Initial research show stimulation of beta-3 receptors, whereby no increased heart rate or blood pressure was observed. It seems that synephrine induces lipolysis and stimulates similarly to caffeine. Some have also observed that synephrine suppresses appetite and increases the metabolic rate.

Titanium Dioxide , also known as titania, has many uses. It is used as coloring or pigment, sunscreen, and in cosmetics. It has photocatalyst effect that kills bacteria and decomposes the toxins which are produced when the bacteria is killed. Its antibacterial effect is continuous even when bacteria are still propagating. It is commonly used in mineral cosmetic products which help protect the skin and fights pimples and skin imperfection. It is also an effective sun block and protects against UVA, UVB, and URA rays which cause deterioration of cells and lead to premature aging, and cancer. It also promotes healing of wounds.

Vitamin B6, also known as Pyridoxine, Vitamin B6 is an essential vitamin to aid in the formation of healthy red blood cells and supports more vital bodily functions than any other vitamin. A water-soluble vitamin, Vitamin B6 is needed to release energy from the food we eat. Vitamin B6 cannot be stored in the body, so it must be obtained daily from either food or supplements. Vitamin B6’s role as a coenzyme involved in the metabolism of carbohydrates, fats, and proteins is what makes it important for dieters. Vitamin B6 is also responsible for the manufacture of hormones, red blood cells, neurotransmitters, enzymes, and prostaglandins. Vitamin B6 is required for the production of seratonin, a brain neurotransmitter that controls mood, appetite, sleep patterns, and sensitivity to pain. For weight loss, dieters should include vitamin B6 to increase their metabolism while rounding out a healthy diet.