Bioperine is an extract from the fruit of Piper nigrum L (black pepper) or Piper longum L (long pepper) that contains 95 percent of piperine. Black pepper is a common household spice. Extract from black pepper has also been used extensively as a medicine. To reach the greatest quality during the harvest, the pepper is reaped before ripening and after that is placed to dry under the sun rays. Bioperine is known for its effect to enhance the efficiency of many supplement nutrients. Bioperine acts to enhance the body’s natural therogenic activity – giving the name thermonutrient. This enhancement brings about increased metabolic rate creating demand for supple of many nutrients such as vitamins, minerals, herbals, amino acids. It sets in motion a process that brings about better digestion and faster gastrointestinal absorption.

Caffeine- The bitter, white crystalline xanthine alkaloid caffeine is found in tea, coffee, soft drinks, chocolates, pain relievers, and a variety of over the counter medications. It is a psychoactive stimulant drug that causes increased alertness by stimulating the central nervous system. For the same reason, many people feel more energetic after consuming it. It even elevates the mood but these effects do not last for long. The effects of caffeine usually last for about five to six hours, though caffeine sensitivity varies from person to person. It has been found that people who consume lot of caffeine on a daily basis soon develop less sensitivity and may need to increase their intake to enjoy the same effect. Being a diuretic, a person consuming caffeine may have to urinate more often.

Guggulsterone- Commiphora wightii, or the so called Guggul tree is a flowering shrub or rather a small tree which can grow up to a size of 4 meters. Once very common in India, it is now there listed as endangered, but not in northern Africa or elsewhere in central Asia. It was very popular in the Indian Ayurvedic medicine, but also currently in the western medicine for treating of heart problems. The hydrocarbon secretion of Guggul contains a plant sterol, guggulsterone, which in the human body seems to act as an antagonist to the farnesoid X receptor. Furthermore, guggulsterone is active in increasing the natural thyroid production. This in turn stimulates the metabolism and may raise the body temperature, burning stored excess fat.

Synephrine, a semi-selective sympathomimetic, is used to stimulate the adrenaline system. Also known as ‘zhi shi’, green orange or bitter orange; it is a chief, active constituent found in the fruit belonging to the plant, Citrus aurantium. Synephrine is not only similar to ephedra in its chemical composition but also serves the same benefits as caffeine or ephedrine. However, it mildly stimulates the fat metabolism without causing any of the side effects associated with ephedra based products. The best advantage of using Synephrine is that it increases the metabolic rate without affecting the hemodynamics. Thus, it is comparatively much safer than ephedra. Since Synephrine promotes weight loss and supports thermogenesis, Synephrine supplements are an ideal solution for dieters and weight watchers. The total intake should be between 2 to 10 mg. per day.

Yohimbe is an evergreen tree which grows in Africa. Traditionally yohimbe is used as an aphrodisiac but it also acts as a powerful antioxidant. It’s usually taken in the form of tea or capsules or tablets. It is also used for impotence, depression, sexual problems in both men and women, in high blood pressure, low blood pressure and for chest pains. Yohimbe bark is also used to treat fever, cough and leprosy. It is also used as an anesthetic to dilate pupil, to prevent heart disease and as a hallucinogen. Yohimbe also helps in weight loss as it contains nor-epinephrine which increases metabolism. Yohimbine an active ingredient taken from bark of yohimbe is used in drugs to treat various disorders.