Caffeine is the most widely available legal psychoactive stimulant drug. Also known as theine, methyltheobromine and trimethylxanthine, this xanthine alkaloid is not only found in coffee beans, but also in guaranine that is derived from guarana, mateine derived from mate, theine which is found in various teas and the kola nut, which is the base flavor of various Cola soft drinks. It stimulates the central nervous system, where it restores alertness and wards off drowsiness. Caffeine is also know to display certain diuretic properties, is an ergogenic, an atagonist of the adenosine receptors, and a cAMP levels increasing factor. It seems that caffeine helps prevent the onset of Parkinson’s disease and in the long run lowers the possibility of developing a heart disease.

Citrus Aurantium is the Latin name for a citrus tree which grows bitter oranges. Traditionally being used by Chinese medicine and herbologists, the extract of the orange and the peel was used as a dietary supplement in concoctions with other herbs to suppress appetite. While other active ingredients of the citrus aurantium may contribute and even promote the effect, the main ingredient used in all weight loss products is synephrine, an alkaloid similar to ephedrine. It is a phenethylamine; it influences the alpha1 adrenergic receptor, constricting blood vessels, additionally increasing the heart rate and the blood pressure. In most cases the use of synephrine is paired with a diet and body building plan, where weight loss and muscle building is essential.

Synthetic Guggulsterones improve the metabolism by increasing the thyroid hormones that influences the triiodothyronine (T3) hormones. It also activate the lypolytic enzymes the helps the burning of fats. Synthetic Guggulsterones is effective for weight loss without raising the heart rate. It also helps maintain the ideal cholesterol level within the normal range. It decreases the LDL cholesterol and triglyceride (TG) levels. Synthetic Guggulsterones also acts as a potent anti-inflammatory agent because of its myrrhanol A content. It also helps reduce acne because it contains tetracycline that is commonly used as an antibiotic in treating acne. It also reduces oxidative stress by decreasing the lipid peroxidation.

Yohimbe, which when ingested, the body converts to yohimbine and assimilates it into the bloodstream. Yohimbe comes from the bark of a tree that grows primarily in Africa. Yohimbine, an alkaloid, is the primary active ingredient of yohimbe. Yohimbe is commonly used as an aphrodisiac and antioxidant. Yohimbe is also used as a vasodilator, which means that it increases blood flow to the extremities and appendages, this is one of the main reasons why it is found in many sexual aids.