Alpha Lipoic Acid- In first clinical trials, alpha-lipoic acid (ALA), managed to restore full liver function to 95% of the acute and severe liver damaged patients, when administered intravenously. Curative effects of ALA have been defined by the modulative regulation in eukaryotes. Lipoic acid has shown the ability to promote and boost the absorption of glucose to cell membranes; furthermore laboratory studies have shown that it can reduce triglycerides in blood. Besides the obviously high efficacy as an antioxidant, ALA has shown to be able to prevent vitamin C and vitamin E deficiency, the use as a chelator is still in the test phase; ALA in combination with L-carnitine shows improved mental performances in tests, paired with a postponed structural mitochondrial decay, making it a candidate in combating Alzheimer’s and Parkinson’s diseases.

Bitter Melon Extract is a vine the fruit of which is one the most bitter of vegetables. This Asian staple has been used for hundreds of years for such ailments as sluggish digestion, dyspepsia, and also constipation, although it can sometimes make ulcers and heartburn worse. It is a mild inflammation modulator and a demulcent. So it rarely has such a negative effect. It is used by both Asians and Colombians for the prevention and treatment of malaria. Studies have shown that it does have anti-malarial activity.

Chromium Picolinate , which is chromium combined with picolinic acid is the most easily absorbed form of chromium, an essential trace mineral that is essential to the body's production of insulin. Insulin is a hormone that stabilizes the body's blood sugar level.

Coleus Forskohlii or otherwise known as Plectranthus barbatus and Indian Coleus is a perennial plant native to tropical regions of Asia and Africa. In Kenya the leaves of the plant have been traditionally used as toilet paper. Ayurvedic medicine lists the coleus species as treatment for various ailments of the urinary tract, spasmodic pain and even heart disease. In the extract of the C. forskohlii is the compound forskolin, which has found wide usage in body building and weight loss circles. It is supposed to increase thyroid hormone production, increasing the metabolic rate. Further data suggests that forskolin may also be responsible in increasing cAMP levels and associated metabolic activities, such as stabilization of insulin levels, relaxation of smooth muscles and promotion of thyroid functions.

D-Pinitol is found in the leaves of a plant called Bougainvillea spectabilis. It is a form of B vitamin inositol. D-Pinitol is widely used for its property of acting like insulin. It is used by diabetic patients as it does not add calories when consumed and is able to reduce blood glucose levels which are important for a diabetic patient. It is also used in treatment of neurological disorders, syndrome X and certain pre-diabetic conditions. It is used in sports nutrition as it improves glucose metabolism. This improves the storage of glycogen and helps increase energy levels, endurance and muscle mass. Because of their ability to increase muscle mass it’s widely taken by body builders and is also used to treat people suffering from muscle wastage.

Guggulsterone- Commiphora wightii, or the so called Guggul tree is a flowering shrub or rather a small tree which can grow up to a size of 4 meters. Once very common in India, it is now there listed as endangered, but not in northern Africa or elsewhere in central Asia. It was very popular in the Indian Ayurvedic medicine, but also currently in the western medicine for treating of heart problems. The hydrocarbon secretion of Guggul contains a plant sterol, guggulsterone, which in the human body seems to act as an antagonist to the farnesoid X receptor. Furthermore, guggulsterone is active in increasing the natural thyroid production. This in turn stimulates the metabolism and may raise the body temperature, burning stored excess fat.

Gymnema Sylvestre has been naturally found in southern and in central India and here they are utilised in traditional medicines for about 2000 years. In the historical Indian text, this is called as gurmar, where this word means sugar destroyer that provides an indication that these are used in the medicine. This is utilised for reducing the glucose absorption which takes place inside your body and even declines the foods sweetness, this could be best suited for those people who want to reduce their weight as well as for those who wants to decline the sugar level which is present in the blood. This is also utilised in Ayurvedic medicine.

Selenium is a trace mineral that plays an important role in several metabolic pathways such as glutathione-peroxidise pathway. Selenium works with Vitamin E which gives its strong antioxidant effects and improves the immune system. It protects the body from prematurely aging. It also help prevent free radical damages that may cause heart diseases and cancer. It is essential in the proper function of the thyroid hormones, and promotes efficient metabolism. It is also beneficial in the reproductive health particularly of men because it facilitates in the sperm production, and prevents infertility. Selenium also helps reduce inflammation which is beneficial to those with rheumatism to reduce pain.