Caffeine is of course a major component of every day drinks such as tea and coffee and is also included in EntroVex. It is claimed that over 70% of the American population take more than 300 milligrams daily. As well as in familiar drinks it is used in energy drinks such as Red Bull as well as in many over the counter analgesics and other medication. Medically it is a as trimethylxanthine, useful as a heart stimulant and it also works as a mild diuretic. It works in the same way as certain drugs, the amphetamines, cocaine, and heroin, all of which work on the action of the brain although in a milder way, and like them it is addictive.

Citrus Aurantium, More commonly called "bitter orange", which is taken from unripe oranges. Research shows that citrus aurantium can increase the metabolic rate without affecting heart rate or blood pressure, breaks down fat, burns calories and may act as an appetite suppressant.

Synthetic Guggulsteroneswere first intended for use as a drug and is now used as a weight loss product and weight management product with the possibility of some side effects. More studies need to be done on this.

Yohimbe (Pausinystalia yohimbe) is a plant which is well known for an alkaloid obtained from it called yohimbine. Its extracts are used as an over the counter pychoactive drug. It acts as an aphrodisiac effective in the treatment of male impotence and sexual dysfunction. Studies have also indicated its efficacy in the treatment of type-2 diabetes. It is quite well known among the body building community. This fame is because of the belief that it can lower fat tissue transdermally. It is also efficacious in conditions where there is lack of saliva production in the mouth, and also in post traumatic stress disorder.