Beta-Alanine, or rather beta-alanine and 3-aminopropanoic acid, is also considered the only naturally occurring beta amino acid, despite being part of larger bioactive molecules like beta-peptides. Beta-alanine is a rate limiting precursor to the dipeptide carnosine, which means that carnosine levels depend on the available amounts of beta-alanine. Carnosine is abundant in brain tissues and muscles. It has been observed that supplementation with Beta Alanine in fact does increase the levels of carnosine, which resulted in athletes experiencing less fatigue and allowing them to boost the amount of muscular work, i.e. the training that can be done. In clinical trials conducted over ten weeks with supplementing Beta Alanine to test subjects, intramuscular carnosine levels were measured at eighty per cent higher levels than before the test.

Betaine was named this due to the source it was discovered in, Beta vulgaris or sugar beets, is an organic compound that is deemed related to trimethylaminoethanol, or choline. To diversify it from other betaines, trimethylglycine is often called glycine betaine as well. Humans generally ingest betaine through their diet, because it is high in content in wheat, whole wheat, shellfish, sugar beets and spinach. It can also be formed in the human body out of choline. As a potential methyl donor, trimethylglycine, or TMG for short, is in the same provider group with Vitamin B12, the folic acid, choline and S-adenosyl methionine, or SAMe. TMG also plays a vital function in the production of carnitine, furthermore it works in protecting kidneys and the liver.

Caffeine is a methylated xenthine discovered in 1819 by Friedrich Ferdinand Runge, a German chemist. Sources of Caffeine include beans, fruit and leaves of some plants. Caffeine available for human consumption is most commonly extracted from the coffee plant cherries and tea bush leaves, as well as foods and drinks that contain products derived from the kola nut. Caffeine can temporarily reduce the sensation of being tired; however, this does not mean that it eliminates the need for sleep. Generally, twenty five to fifty milligrams of caffeine is enough for most consumers to report an increase in alertness and arousal. Caffeine should be not be consumed by those with fecal incontinence as it relaxes the internal anal sphincter muscles.

Calcium is a mineral that plays an important role in the development of the human body. It is common knowledge that calcium is important in preventing osteoporosis. However, calcium also provides structural support in the development of muscles. Deficiency in calcium could cause obesity because it triggers the release of parathyroid hormone that stimulates the production of fats in the body and inhibits its breakdown. It also reduces the blood pressure. Calcium also has the ability to fight colon cancer by binding itself with cancer cells to inhibit its growth and progression. It is also beneficial to women suffering from PMS or premenstrual syndrome such as depression, mood swings, anxiety, water retention, breast tenderness, and headaches.

Choline is a water soluble essential nutrient of every human cell which belongs to the Vitamin B family. It helps in the transfer of fat-based nutrients and waste from the cells. It plays a vital role in maintaining mental health and is used in treating brain disorders and Alzheimer’s disease. It assists the transfer of messages to and from the nerves and reduces inflammation. A choline deficiency results in insomnia, problems with memory, fatigue, nerve-muscle problems, inability of the kidneys to concentrate urine properly, accumulation of fats in the body, cardio vascular and liver problems. Wheat germ, soy products, cauliflower, peanuts, oats, potatoes, lentils, flax and sesame seeds are rich in choline. It is also found in egg yolks, veal, chicken, beef and turkey livers.

Citrulline is an a-amino acid. Its chemical formula is H2NC(O)NH(CH2)3CH(NH2)CO2H. It is a key intermediate in the urea cycle, the pathway by which mammals excrete ammonia. Commercially it is synthesized by many different processes and naturally it is found in significant quantity in rind of watermelon. Some recent studies show that use of citrulline relaxes blood vessels. It is also sold as a supplement in the form of citrulline malate for athletes to reduce muscle fatigue; these supplements are shown to be effective in preliminary clinical trials. In some studies it is found that patients with arthritis have detectable antibodies against proteins containing citrulline.

Creatine Ethyl Ester is an organic compound formed by the reaction of alcohols and carboxylic acid. The standard creatine monohydrate is effective in increasing the muscle strength, lean muscle and endurance. Creatine ethyl ester is absorbed by the ability of the cells as the body does not absorb it properly. This is the reason that creatine is taken in large dosages. Creatine ethyl ester is a monohydrate associated with ester. This ester has the significance as it is found in the animals fat tissue. Creatine supplements are blended with protein powder. However, if it is taken for a longer period, the body stops producing it naturally and completely depends on the supplement. The creatine monohydrate shows no reports having side effects. Women also take creatine, but consulting the doctor is recommended. Ethyl ester decreases the amount of retained water as it is made with typical fatty acids that occur naturally. Hence, less creatine is stored as water weight out of the nutrient pocket.

Creatine Monohydrate is an organic acid that is naturally found in humans. First discovered in 1832, the primary function of creatine monohydrate is to help in supplying energy to the muscles. About half of the stored creatine monohydrate in the body comes from food sources, mostly meat. Vegetarians tend to show lower levels of creatine monohydrate since vegetables don’t contain this acid. However since meat tends to contain high levels of saturated fat which is not good for the heart, one way in which creatine monohydrate can be made available is through supplements. In fact many body builders take creatine supplements to help in increasing muscle mass. Creatine monohydrate has also been shown to cause slight increase in strength in those with neuromuscular disorders and is now being considered as a therapy for several diseases like Parkinson’s, Huntington’s etc. especially because it is considered safe and so far has exhibited no side effects.

Di-Creatine Malate is a compound made up of creatine salt that is bonded together with malic acid. It increases the availability of creatine in the body; this ensures the efficient absorption and use of creatine. The compound results in a greater production and quick replenishment of adenosine triphosphate or ATP. It helps in increasing strength in the cellular level that allows the production of explosive bursts of power. It also aids in increasing endurance by acting as lactic acid buffer. Di-Creatine Malate helps in the formation of muscle mass, decrease fat tissue, and improves cell volume. It also does not cause upset the stomach because it is easily absorbed by the intestine.

Glucuronolactone is formed in the body by the liver and well known for its supply of energy and provides an increased feeling of well being in the body. It also improves time taken in reaction to different stimuli, improves memory and concentration power and overall grey cell performance. Glucuronolactone is a natural detoxifying agent that helps to get rid of harmful substances from the body by making them water soluble. Being an important component of most connective tissues in animals, Glucuronolactone supplements help in the cure of arthritis. Being a popular ingredient in most energy drinks, Glucuronolactone reduces sleepiness and driving mishaps that are sleep related. Rumors state that Glucuronolactone was initially banned by the US Government.

Glycocyamine was sought after because as much as a quarter of the world’s population is unable to supplement creatine, more accurately, the supplementation of regular creatine monohydrate had no effect whatsoever. Glycocyamine is a creatine metabolite, missing just a methyl group. Glycocyamine is guanidinoacetic acid and creatine is methylguanidinoacetic acid. Interestingly enough, glycocyamine is processed by the liver and metabolized into creatine, which allowed the rest of the world to supplement creatine as well. Unfortunately the supplementation of glycocyamine also meant that many methyl groups otherwise needed by the body would be now used up by the synthesis of creatine. For that reason it is generally recommended to supplement glycocyamine together with betaine, in order to provide enough methyl groups for all purposes. The commonly suggested ration is four parts betaine, one part glycocyamine, hence a four to one ratio.

L-Tyrosine is a non essential amino acid occurring in the body. L-Tyrosine may be created from the synthesis of phenylalanine which is also an amino acid. It is one of the building blocks of proteins in the body. It is also a precursor for several neurotransmitters such as L-dopa, dopamine, epinephrine and norepinephrine. It helps treat and prevent illness such as Parkinson’s disease, Alzheimer’s disease, depression and other such mood disorders. It also helps protect the body from free radical damages. It also helps protect the skin from UV rays damages on the skin by aiding in the production of melanin. It also helps in increasing the metabolic rate that speeds up muscle building and fat loss. It also increases the endurance.

Magnesium, which is a mineral used by the body to help maintain muscles, bones, and nerves. Magnesium is also needed for energy metabolism and protein synthesis.

Potassium is an electrolyte, a substance that maintains the fluid levels in the body. It is helpful in regulating blood pressure and heart function. Intake of potassium can benefit people suffering from hypertension. Research has found that a potassium supplement intake decreased incidence of stroke by 60 percent. It neutralizes acids and restores alkaline salts to bloodstream.  It acts along with sodium cells to maintain or restore membrane potentials. Potassium is also vital for nerve functioning and cardiovascular, and regulates nutrients’ transfer into cells and adds to muscle energy. It also helps recuperative powers, besides regulating water balance. Potassium is beneficial for eliminating wastes. It is helpful in controlling headaches and convulsions, and quickens healing of cuts, bruises and other injuries.

Sodium is the element that has the atomic number 11 in the periodic table and is commonly known as the main component in the table salt, together with chloride. Interestingly enough, it is probably the one dietary component which does require limitation rather than supplementation, since that average daily nutritional requirement is around half a gram per day. This most popular food seasoning, salt, is providing the most common source of sodium and chloride in human diets, but is generally overused and may cause health problems, such as high blood pressure, if consumed overly generously. The suggested dose of table salt, or rather the upper limit portion, would be somewhat less than 6 gram per day, according to the Dietary Guidelines for Americans, referenced by FDA. In the UK this limit is set at four grams per day.

Taurine is basically an amino acid that is not formed by the body. It is found freely in the bloodstream and in tissues. It is also found in abundance in the skeletal system, the heart and the nervous system. During times of extreme physical activity, the amounts of taurine in the body are depleted. Taurine has a tendency to act as a metabolic transmitter and can also be used as a detoxifying agent. It has been added to a number of products for infants as well. The popular energy drink ‘Red Bull’ is well known for its taurine content. Taurine is also recommended for use by people who suffer from manic depression. Taurine is tested and has proven to be an extremely safe dietary supplement.

Vinpocetine is a compound that is derived from a substance found in the leaves naturally called vincamine. Vinpocetine was established in 1960s. This was available in Japan and Europe with prescription and in Canada and the United States it was available in health food stores as well as online as dietary supplement. Vinpocetine increases the blood circulation and reduces the impairment in the brain. Vinpocetine is given to people suffering with Alzheimer’s disease as a complementary treatment. It enhances the use of oxygen in the brain and protects the brain cell from damage. Thereby it works in enhancing the blood flow towards the brain. Vinpocetine prevents strokes and memory disturbances. Vinpocetine is useful in improving, hearing, eyesight and also in alleviating problems that are connected to menopause. Vinpocetine has effect on the damaged areas in the brain and is also an anti-oxidant. So it shields the brain from aging. The dosage recommended is 5mg tablet twice or thrice daily.

Vitamin B1, or rather the Vitamin B complex, is a group of vitamins that are all soluble in water and very often coexist in food sources. While every single Vitamin from the B complex group has a name, they are very often referred to by the number added to the Vitamin B group name, like Vitamin B1, which is thiamine, or Vitamin B2, which is riboflavin. Some other compounds have been added to the Vitamin B group at some time, but were later dropped, like adenine, orotic acid or adenosine monophosphate, where later research found that they are either synthesized by the human body or simply no Vitamins. Vitamin B complex supports the metabolism rate, maintains muscle tone and skin, raises functions of the nervous system and the immune system, promotes red blood cells and cell growth and division and much more.

Vitamin B12- Also called Riboflavin, B2 is a water absorbed vitamin of which the body must replenish its supplies each day as it cannot be stored. It is necessary for the production of red blood cells and, like the other B vitamins, it works at supporting it supports energy production by helping in the metabolism of various foods.B2 is required for healthy skin as well as hair growth, the nails and has a role in regulating the activity of the thyroid gland. It is also necessary in order that the body can process amino acids found in proteins and fats and to activate vitamin B6 and folic acid.

Vitamin B2 is a water-soluble vitamin with no known toxic effects. Riboflavin (Vitamin B2) is necessary in the oxidative process of metabolism. It is also sometimes used to correct certain enzyme deficiencies and improve mental processes.

Vitamin B3 is also known as Niacin or nicotinic acid. It helps in the conversion of carbohydrates into glucose that serves as fuel for energy. It also helps the body in metabolizing fats and proteins. Niacin also helps in the production of hormones necessary for the body to function properly. It is also effective in improving the circulation in the body. It lowers cholesterol, triglycerides and blood sugar level. It also helps in the treatment of coronary artery disease. It also helps in regulating the blood sugar level. Niacin also helps prevent the Pellagra disease, which causes digestive problems, diarrhea, dermatitis, hyper-pigmentation, amnesia, dementia, delirium, and even death. Niacin also helps prevent Alzheimer’s disease, diabetes, and is also effective in treating acne.

Vitamin B5, also called Pantothenic acid, which is a water-soluble vitamin required by the human body. Vitamin B5 is needed to form coenzyme-A (CoA), and is vital in the metabolism and synthesis of carbohydrates, proteins, and fats.

Vitamin B6- There are three traditionally considered forms of vitamin B6: pyridoxal (PL), pyridoxine (PN), pyridoxamine (PM). The phosphate ester (PLP) has a leading role in metabolism of human body. It is obtained from the diet since humans cannot manufacture it. PLP is crucial in over 100 enzymes that enable important chemical reactions in the human body. In the brain, the manufacture of neurotransmitters like serotonin from tryptophan is made possible by PLP. PLP is also a coenzyme in the production of the iron coating component of hemoglobin called heme. Signs of vitamin B6 deficiency include irritability, depression and confusion, inflammation of the tongue, sores or ulcers of the mouth and the skin at the corner of the mouth.

Vitamin B9 or Folic Acid, is essential as it assists the formation of red blood cells in the body and genetic material within every cell. It helps in metabolism of proteins and prevention of anemia and is vital for cell growth and division. Folic acid is an important nutrient for pregnant women to prevent congenital malformation in the fetus. It reduces the risk of brain and spinal cord defects, heart defects, limb defects, urinary tract abnormalities and cleft palate in the fetus. It is highly beneficial if taken prior to and during the first month after conception. In men, folic acid reduces chromosomal defects in the sperm. Spinach, lettuce, peas, beans, sunflower seeds, asparagus, baker’s yeast, fortified cereal products and liver are rich in folic acid.

Zinc is a mineral found in most cells in the human body. It plays an important role in stimulating enzyme functions. It improves the immune system that protects against bacterial and viral infections. It also promotes healing of wound. Zinc helps in maintaining a normal growth and development during pregnancy, childhood and adolescence. It also has antioxidant properties that prevent cell damage caused by free radicals that may lead to premature aging, heart problems and even cancer. It aids in cell growth, renewal, and repair. Zinc increases muscle growth and improves endurance. It also helps cleanse and get rid of toxins that accumulated in the body.