Caffeine, a central nervous system stimulant used in D4 Extreme Weight Loss as an aid to stay awake, for mental alertness due to fatigue or, in combination with other ingredients for pain relief, and as a power and energy accelerate. Caffeine is available alone as a non-prescription drug over the counter medication, in combination with other non-prescription drugs, and in prescription drug combinations for relief of pain and headache. Like Ephedra, caffeine acts to increase mental alertness while providing additional energy for weight loss and exercise training. Caffeine is more than a stimulant as it goes deep into muscles to provide long lasting power while delaying the onset of muscle fatigue. Also great before working out, caffeine fights fatigue and helps you get ready for your workout. For dieters feeling sluggish that need just a little something extra to get them through the day, caffeine is the obvious no-calorie stimulant solution. Many products containing caffeine anhydrous contain as much caffeine as one or two cups of coffee. It is recommended to limit the use of caffeine containing medications, foods, or beverages while taking caffeine supplements as excess caffeine intake may cause nervousness, irritability, sleeplessness and occasional rapid heart beat.

Clary Sage Powder, also known as Salvia sclarea, is basically a biennial herb. It is a herb native throughout Europe and central and east Asia. Though, it was historically found in France, Switzerland, Italy and Syria. It reaches a height of one meter at the time of maturity. It has wooly texture leaves. The flowers on this herb appear in clusters on its stem and are often of the color pink, white or pale purple. Salvia sclarea is known to have an odor that appeals to some while at the same time are very unpleasant for the others. Majority of the salvia sclarea cultivation is done for the perfume industry in England, France and southern Russia. A lot specialty stores and scent shops sell the distilled essential oil obtained from salvia sclarea.

Evodia Rutaecarpa is used to prevent digestive disorders and has anti-inflammatory characteristics. It also keeps the blood thin so that the nutrients pass through the body with ease.

Octopamine is related to noradrenaline. Octopamine was discovered by Vittorio Erspamer, an Italian scientist in 1948. Octopamine has a significant role in mollusks and is the central nervous system in snail. Octopamine also has a vital role in memory and learning in the fruit fly and honey bee. Octopamine is also useful for the firefly in releasing the light production. Octopamine mobilizes releasing fat in mammals and this has developed into promotion as a slimming aid on the internet. However, there is no apparent evidence about Octopamine facilitating weight loss. Octopamine also significantly increases the blood pressure in combination with stimulants such as weight loss supplements. This is extensively used in energy demanding insects such as spiders, lobsters, crabs and crayfish as their behaviors also include egg-laying, jumping and flying. Among vertebrates, Octopamine substitutes norepinephrine and as well exhibits common side effects. Octopamine is sited in the locust jump such that it modulates the muscle activity allowing the leg muscles to contract effectively.

Passion Flower- Passion vines, or Passiflora, are a 500 species strong genus of flowering plants that all belong to the family of Passifloraceae. While most of the plants are classified as vines, there are also some shrubs and herbaceous plants that can be found. With the exception of Europe and Africa, as well as Antarctica, these plants are found all over the rest of the world. While the passion flower is mostly known for the Maracuja, or Passiflora edulis, the passion fruit, the vines of some species in this genus are known to have properties that have been used by Native Americans for treatment of insomnia, epilepsy and hysteria, as noted with Passiflora incarnata. Many other species contain beta carboline harmala alkaloids, which function as monoamine oxidase inhibitors and are powerful antidepressants.

White Willow Bark, more accurately the bark of the deciduous tree, has been known since the ancient times for its medicinal properties. Already the ancient Egyptians, but also Hippocrates, Assyrians and Sumerians have recognized that the powder extracted from the white willow bark is a very potent remedy for fever, but active against pains and aches as well. Salix alba, which is the Latin name for the white willow, contains an active alcoholic beta glycoside that contains D-glucose and is named salicin. Salicin is metabolized in human body to salicylic acid and is very closely related to aspirin. When ingested it has a quinine like bitter taste. Salicylic acid is anti inflammatory and keratolytic, and is commonly used as an additive in weight loss products.