Caffeine is a powerful and very common alkaloid supplement used in D&E Nature's Super Cap primarily to increase the body’s ability to lose weight quickly, boost energy and stimulate the brain into more activity with better clarity. It also fuels the body’s metabolism for increased fat burning qualities. This allows users to have more stamina for exercise and more focus for weight loss initiatives. Caffeine anhydrous is found naturally in many different beans and plants and works successfully as a stimulating supplement for those needing increased energy, focus, and alertness. When taken as a supplement for health or weight loss reasons, caffeine anhydrous should not be combined with other traditional forms of caffeine, such as soft drinks, energy drinks, coffee, or tea, because the supplement form is concentrated and powerful in itself.

Cayenne, which contains Capsaicin, a thermogenic substance. A thermogenic raises your core temperature, which allows you to burn more calories from food, particularly when eating a high fat meal.

Green Tea Extract- By increasing the body's metabolism, it is widely believed that green tea extract largely aids in weight loss.

L-Phenylalanine gained notoriety with the aspartame controversy where extensive internet bombardment against the artificial sweetener prompted a thorough cleaning by The Coca Cola Company and other interest groups. Now it seems that aspartame has more benefits to health than aspirin. L-Phenylalanine is an essential alpha amino acid that is deemed analgesic and antidepressant. It is hydrophobic and nonpolar, one of only twenty common amino acids that are used to produce protein as coded by the DNA. L-Phenylalanine can also convert into L-Tyrosine, which can then become L-DOPA, going forth to become norepinephrine, dopamine or epinephrine. Phenylalanine is very often found in foods, protein rich foods like meat, milk and milk products, poultry and fish, but also as already mentioned in the artificial sweetener aspartame.

Mormon Tea is a tea extracted from plant Ephedra sinica. It has been used traditionally for treatment of asthma, common cold and hay fever. In Chinese medicine Ephedra extracts are used as a stimulant that constricts blood vessels, and increases blood pressure and heart rate. Mormon Tea is used as a stimulant and a thermogenic due to its ephedrine and pseudoephedrine content. Some research also shows that it can help in weight loss. Mormon Tea can also increase brain activity and athletic performance; however some studies suggest avoiding use of it because it may have side effects related to heart disease.

NADH or nicotinamide adenine dinucleotide hydrogen is a double nucleotide and is the reduced form of NAD. It acts as an electron carrier in the body. Chemically it is composed of two nucleotides adenine and nicotinamide joined through their phosphate groups.

Theobromine, which is a mild diuretic and mild stimulant. Theobromine can be found in cocoa and chocolate products. Theobromine is most commonly used for its diuretic effect.