Calcium, a mineral vital to the human body, Calcium is necessary for many bodily functions, such as muscle contraction, and proper heart function.

Magnesium is another mineral which is deemed essential for all biological life. As an essential part of basic nucleic acid, magnesium ions, together with phosphate ions, are also required for over 300 catalytic reactions of enzymes. Any enzymes synthesizing or utilizing adenosine triphosphate require a magnesium ion. Incredulously enough, magnesium deficiency is the most widespread deficiency, affecting a third of the population in the United States only, with third world countries surpassing the count easily. Being also essential, together with calcium and phosphorus, in the skeletal structure, magnesium deficiency is viewed as a main factor in ailments such as osteoporosis. Naturally available through cereals, green leafy vegetables, nuts, spices, tea, cocoa and coffee, magnesium is available as a supplement in magnesium oxide and magnesium citrate form, whereby the latter is viewed as more bioavailable.

Phosphate (Phosphorus) is the chemical element with the atomic number 15 in the periodic table. It is not found as a free element anywhere in the world. In biology and biochemistry it may be the most important element, being present in all living cells of living species. It is present in the DNA, in the RNA, in ATP, but is also found in cell membranes in form of phospholipids. It is also present in the bones, where it builds calcium phosphate salts, responsible for strong bones. Apatite is a collection of phosphate minerals which are generally found in bones and teeth; namely bromapatite, fluorapatite, chlorapatite and hydroxyapatite. Several phosphates are being added to body building supplements and powders, intended to aid in skeletal and cellular strength improvement.

Vitamin D is actually a group of prohormones, all fat soluble, whereby ergocalciferol, or Vitamin D2 and cholecalciferol, also known as Vitamin D3 are the most common forms. The Vitamin D3 form is made when human skin is exposed to UV B radiation. The active form of Vitamin D is calcitrol and it is required in the body to manage phosphorus and calcium levels, but, among other functions, to affect anti tumor activity, immunomodulatory functions and much more. Vitamin D, or more accurately calcitrol, is being bound to a carrier protein, which allows it to be transported throughout the body to the various destinations. The Vitamin D receptors, steroid and thyroid hormone receptors, can be found in most organs, including the brain, skin, heart, breast, prostate and gonads.