Bioperine is an extract from the fruit of Piper nigrum L (black pepper) or Piper longum L (long pepper) that contains 95 percent of piperine. Black pepper is a common household spice. Extract from black pepper has also been used extensively as a medicine. To reach the greatest quality during the harvest, the pepper is reaped before ripening and after that is placed to dry under the sun rays. Bioperine is known for its effect to enhance the efficiency of many supplement nutrients. Bioperine acts to enhance the body’s natural therogenic activity – giving the name thermonutrient. This enhancement brings about increased metabolic rate creating demand for supple of many nutrients such as vitamins, minerals, herbals, amino acids. It sets in motion a process that brings about better digestion and faster gastrointestinal absorption.

Citric Acid is found in several citrus fruits, including pineapples, limes, gooseberries, plums, peaches, lemons, grapefruit, and oranges. It assists in preventing urinary tract infections. It is also applied as a natural preservative in lieu of chemicals. It helps energy production within the cells. It is a good natural astringent and regulates pH in digestive tract. Citric acid boosts efficient digestive function and helps remove toxins from body. It provides prevention against diarrhea, dysentery, and other bowel diseases. Citric acid assists in breakdown of fatty foods and increasing appetite. It helps eliminate fatigue. Citric acid in a little modified form, potassium citrate, can halt human heartbeat for greater facility during surgery and also is used to leach damaging metals from soil in landfills.

Cyclic Adenosine Monophosphate 3'-5'-cyclic adenosine monophosphate or Cyclic Adenosine Monophosphate, a second messenger that mediates the action of several eptide or amine hormones, is abbreviated as cyclic AMP or cAMP. cAMP is thus vital for varied biological processes and used for intracellular signal transduction in various organisms. This major communicator is a result of the action of the enzyme adenyl cyclase on ATP. As such, cyclic AMP performs many physiological functions and is also responsible for increasing blood glucose levels. Adrenaline that enhances blood sugar levels in the body is able to do so by stimulating cAMP production. Cyclic AMP plays an important role in the following: urine regulation synthesis of flagellar proteins in bacteria hormone release sensory and nerve processes Apart from these functions, it also helps in breakdown of lipids in some organisms to produce energy in the absence of sufficient glucose.

Di-Sodium Phosphate is a white powder that is soluble in water and is highly hygroscopic. It is a phosphoric acid and is hence used commercially. It is wisely used as additive in anti-caking and is as well known as sodium hydrogen phosphate or disodium hydrogen orthophosphate. It is available in anhydrous and hydrated forms. Disodium phosphate is a significant ingredient of product package and can be used as cream of wheat so that the cooking time is quickened. Disodium phosphate is commonly used in the salt form. Disodium phosphate can be taken with large amounts of drinking water. However, nothing should be given orally to a person who is in the unconscious state. Disodium phosphate is not advisable for skin contact. The skin should be flushed immediately with lots of water for minimum 15 minutes. Thoroughly clean and acquire medical attention in case of development of any irritation. Medical attention is advised under any unusual circumstances.

Dioscorea Villosa extract is a medicinal herb commonly knows as the wild yam. It has medicinal properties that help in curing the pain caused during menstrual cycle, stomach cramps, and discomfort from gallstones and rheumatoid arthritis. It has been used fro centuries by the Native Americans. It is also used by herbalists for female and childbirth related problems. Along with herbal medicine, this plant is of great use in the modern medicine as well. It is because of this plant that birth control pills are so commonly and easily available. Its steroid like property explains the vast usage of this plant for medicinal purposes. But consumption of this extract may also lead to a number of side effects. Vomiting, diarrhea, nausea and headache are some of the most common side effects of dioscorea villosa extract.

Evodiamine, a bioactive alkaloid extract from the Evodiae Fructus plant, sometimes called Wu-Chu-Yu. Evodiamine is related to capsaicin, found in cayenne pepper. Evodiamine is a vanilloid receptor agonist, and may enhance lipolytic activity. Evodiamine has been shown to raise the body’s skin temperature and decrease core temperature, which is thought to burn calories and fat for energy.

Glabra, commonly known as licorice, is a root used to extract a sweet flavor from. Licorice is a plant belonging to the legume family, like peas and beans. It takes two to three years after planting for licorice to be harvested in autumn. It requires deep, fertile, well drained soil with a lot of sun to be able to grow. The extract from licorice is produced by boiling the roots with water and then evaporating all the water. This extract is then sold both in the form of solid and liquid. Glabra consists of a sweetener called glycyrrhizin which is many times sweeter than sucrose. It is used in lot cough syrups and in ayurvedic medicine. Candies made from licorice roots are famous all over the world. Hence it is in many pharmaceutical and confectionery products.

Guggulsterone- Commiphora wightii, or the so called Guggul tree is a flowering shrub or rather a small tree which can grow up to a size of 4 meters. Once very common in India, it is now there listed as endangered, but not in northern Africa or elsewhere in central Asia. It was very popular in the Indian Ayurvedic medicine, but also currently in the western medicine for treating of heart problems. The hydrocarbon secretion of Guggul contains a plant sterol, guggulsterone, which in the human body seems to act as an antagonist to the farnesoid X receptor. Furthermore, guggulsterone is active in increasing the natural thyroid production. This in turn stimulates the metabolism and may raise the body temperature, burning stored excess fat.

Horsetail Herb- Horsetail products have been known to increase the production of urine. There is only a small amount of research in humans specifically using horsetail grass stem. Because there is a scientific basis for horsetail working as a diuretic, horsetail likely does increase urine. It is not clear what dose is safe or effective. One study suggests that horsetail may increase the rate of bone formation and aid in calcium deposition into bone. However, this study was limited.

L-Tyrosine is a protein non-essential building block Although non-essential it is important for the structure of body proteins. It has a direct effect on neurotransmitters.

Octopamine, which is a trace amine, recently believed to be a lipotropic for fat loss. Octopamine has low oral bioavailability and is readily broken down by MAOI, as well as metabolized by the gut wall, which may mean it would not work well when taken orally, but more research is needed to prove its positive or negative effects.

Phosphatidylcholine is a key phospholipid constituent of cell membranes hepatic lipoproteins and bile. It is commonly used in cell signaling pathways. Phosphatidylethanolamine can prove helpful in treating Alzheimer. Brains affected by Alzheimer comprise fewer synapses and decreased levels of synaptic proteins, membrane phosphatides, choline and DHA. Phosphatidylethanolamine utilizes pyrimidine and a PUFA (for example, docosahexaenoic acid), which can significantly enhance levels of membrane phosphatide and synaptic protein in gerbil brains. Phosphatidylethanolamine also helps regulate homocysteine. It is synthesized by two pathways, CDP-choline pathway and methylation of phosphatidylethanolamine by phosphatidylethanolamine N-methyltransferase (PEMT). Recent research has suggested that PEMT is a significant consumer of methyl groups from S-adenosylmethionine (SAM) and plays an important role in determining homocysteine pools.

Potassium is an electrolyte, a substance that maintains the fluid levels in the body. It is helpful in regulating blood pressure and heart function. Intake of potassium can benefit people suffering from hypertension. Research has found that a potassium supplement intake decreased incidence of stroke by 60 percent. It neutralizes acids and restores alkaline salts to bloodstream.  It acts along with sodium cells to maintain or restore membrane potentials. Potassium is also vital for nerve functioning and cardiovascular, and regulates nutrients’ transfer into cells and adds to muscle energy. It also helps recuperative powers, besides regulating water balance. Potassium is beneficial for eliminating wastes. It is helpful in controlling headaches and convulsions, and quickens healing of cuts, bruises and other injuries.

Quercetin is a flavanoid derived from plants and is widely used as a nutritional supplement. There are many studies which are being conducted to exactly determine the benefits of Quercetin. It is said to have antioxidant and anti-inflammatory properties and hence is being tested to help curb and cure terminal diseases like cancer. The high intake of fruits and vegetables is good for cancer treatments. Many researchers believe that these qualities of Quercetin are what allow it to be used for treating cancer as well. Quercetin is classified into the IARC group 3; which categorizes food and drugs as that which are not carcinogenic.

Smilax- The genus Smilax includes approximately 300 different species of vines, found in warm regions like South America, North America and the Caribbean. Also known as Sarsaparilla, the roots of the plant are highly effective and thus used in various herbal treatments. For centuries, Smilax has been used by the natives for curing ailments and disorders like sexual impotence, dermatitis, syphilis to name just a few. The plant contains plant steroids called saponin as well as flavonoids. Theoretically, it is believed that the body synthesizes saponin into sex hormones, testosterone and estrogen. Since the plant has flavonoids, it also boasts of antioxidant properties. Smilax dietary supplements are extensively used for strength training and bodybuilding. The best benefit of using Smilax supplements is that there are absolutely no side effects.

Taraxacum Officinale is the most common weed flowering plant found worldwide. The two most common species are Taraxacum officinale and Taraxacum erythrospermum, also known as the dandelion flower and the dandelion parachute ball. A flower head of such a dandelion flower is structured out of hundreds of smaller florets. These biennial or perennial herbaceous plants are native to Europe, the Northern Hemisphere. It has been found out that the flowers of dandelion contain a strong antioxidant, luteolin, which is a flavonoid with diverse properties, such as inflammation inhibitor, immune system modulator and a carbohydrate metabolism promoter. Chinese medicine has used this plant for centuries for medicinal purposes, usually in form of a tea concoction, applied as a liver detoxifying method. Other uses were listed as inflammation reduction and as a diuretic.

Trimeylxanthine Anyhydrous is a form of caffeine that is found in many energy supplements. This stimulant is very beneficial for those who are looking to increase their energy and stamina levels. Trimelyxanthine anyhydrous is often combined with other ingredients to create various proprietary blends that are sold as weight loss supplements or energy supplements. Trimelyxanthine anyhydrous may also be marketed as a supplement that will bring about greater mental clarity, mental alertness, and focus. You can find this stimulant in both pill form and more potent powder form, although not generally sold alone but found as an active ingredient in other products.

Vinpocetine, a derivative alkaloid of vincamine, is actually semi synthetic in nature. It is an extract from the It is an extract from the periwinkle vinca minor. Vinpocentine is used because it has neuroprotective effects and also helps in enhancing the cerebral blood flow. In Eastern Europe, it is also used as a drug to treat cerebrovascular disorders along with age related memory impairment. It is also extensively marketed as a supplement for vasodilation. It is also used to improve the memory since it plays the role of a nootropic. Vinpocentine is therefore used in supporting brain function. It helps in enhancing concentration and memory by activating cerebral metabolism. In the body building world, vinpocetine is often used a vasodilator. However, no research has been done so far on the effect of vinpocentine in the body building.

Vitamin B3, commonly called Niacin, exists in two main forms, niacin and niacinamide. The niacin form produces a flushing and itching of the skin when taken at higher dosages and this feeling is only temporary.