3, 17-Dihydroxy-Delta-5-Etiocholane-7-One Diethylcarbonate (also called A7-E) is a chemical compound which has shown considerable promise as a fat burner. It increases the basal metabolic rate (BMR) and enhances the function of the thyroid gland. It increases the levels of the thyroid hormone T3 which increases heat generation through non-shivering thermo genesis. It increases the level of malic enzyme leading to the production of oxaloacetate which is rate limiting (its dearth lowers the rate of reaction) in fat metabolism. A7-E also stimulates mitochondrial energy production using fat. In addition to all this, this chemical has a high bioavailability, higher conversion rate and it remains active for a considerable length of time.

Caffeine is a stimulant that is used to stay awake and it gives mental alertness from fatigue. This is used as an adjunct for pain relief and also as energy accelerates. Caffeine is a non-prescription drug easily available as over the counter medication and comes in combination to acquire relief from headache and pain. Caffeine increases the mental alertness by offering the required energy for exercise training and weight loss. Caffeine cannot be considered as a mere stimulant as it reaches deep into muscles and provides power that is long lasting. Caffeine taken before any work out is also great as it fights the fatigue and keeps the person ready for the workout. Dieters also find caffeine as the solution as they feel sluggish. This is a no-calorie stimulant and does its job effectively and quickly. Caffeine anhydrous is found even in one or two coffee cups. However, this limitation is recommended as excess caffeine may result in irritability, rapid heart beat, nervousness and sleeplessness.

Forskolin is an ingredient found in the Indian coleus plant, also known as Coleus forskohlii. It is a labdane diterpene that is currently very popular as a nutritional supplement, predominantly in the body building circles. The ability to raise the levels of cyclic adenosine monophosphate, cAMP, by deploying the enzyme adenylyl cyclase in the cAMP dependent pathway, made forskolin very important. Further benefits of forskolin include reduction of urinary tract infections, in connection with rolipram inhibition of colon cancer spreading, stimulation of proper tanning response with increased skin resistance to sun burns, reduction of intraocular pressure in glaucoma cases and apparently assistance in weight loss programs. Forskolin was observed to increase bone and lean mass as well as testosterone levels in clinical trials conducted with human test subjects.

Lauroyl Macrogol-32 Glycerides~

Piperine, an extract that comes from the fruit of the black pepper plant “Piper Nigrum” and “Piper Longum,” sets the stage for the activities in the body that lead to digestion and intestinal absportion by increasing the metabolic process. It is a pungent substance that has been used in Ayurvedic medicine for treatment of various diseases and is commercially available. Piperine forms monochenic needles, is slightly soluble in water and even more so in alcohol, ether, or chloroform. It significantly enhances the body’s ability to absorb nutrients into the blood stream, and supports the body’s natural thermogenic activities. It inhibits human CYP3A4 and P-glycoprotein, which are enzymes that are important for transport of xenobiotics and metabolites. Piperin has been found to stimulate skin pigmentation when exposed to UVB light. Caution should be used by those on other medications if taking this extract because of piperin’s effects on drug metabolism.

Yohimbine HCL is a bark and is appropriate for sexual dysfunction. This is the best for erection problems as it has alkaloids. The alkaloids possess medicinal properties and are used in drugs. Yohimbine meant the chemical found on the Yohimbe bark. This belongs to the chemical family called alkaloids. Yohimbine effects are impressive. Yohimbine is used since many centuries for sexual enhancement. This bark is now sold in alkaloid concentrations such as 4%, 8% and so on up to 20%. The higher is the concentration, the more is the potent. There are companies promoting it for weight loss as well. Yohimbine HCL exhibits side effects in the form of anxiety. This bark is dangerous when consumed in excessive amounts. Higher oral doses create numerous side effects like high blood pressure, rapid heart rate and over stimulation. It also causes sleeplessness and insomnia in users. It is best to take this only after the consultation of a physician or should be taken in minimal quantities.