Caffeine is the most widely available legal psychoactive stimulant drug. Also known as theine, methyltheobromine and trimethylxanthine, this xanthine alkaloid is not only found in coffee beans, but also in guaranine that is derived from guarana, mateine derived from mate, theine which is found in various teas and the kola nut, which is the base flavor of various Cola soft drinks. It stimulates the central nervous system, where it restores alertness and wards off drowsiness. Caffeine is also know to display certain diuretic properties, is an ergogenic, an atagonist of the adenosine receptors, and a cAMP levels increasing factor. It seems that caffeine helps prevent the onset of Parkinson’s disease and in the long run lowers the possibility of developing a heart disease.

DL-Phenylalanine works with body’s natural ability to ease pain. It assists in increasing the lifespan of brain chemicals that relieves pain. It is particularly effective in reducing pain caused by arthritis and aching muscles. DL-phenylalanine can treat persistent pain by stimulating nerve pathways in the brain responsible for controlling pain. Its effect increases if used with prescribed pain killers. DL-Phenylalanine, which is a combination of essential amino acid L-phenylalanine and D-phenylalanine, blocks an enzyme in the nervous system that enhances pain signals. This disturbance of pain signals causes the body’s healing mechanisms to start working faster. Use of DL-phenylalanine is also reported to have helped people in improving their mood and in treating depression. This is because a higher proportion of production of brain chemicals dopamine and norepinephrine, if went out of balance, cause depression, stress and frustration. Increasing the levels of these chemicals has an anti-depressant impact in the body.

DL-Phenylalanine is a a-amino acid. The biological functions of D-amino acids remain unclear although some, such as DL-phenylalanine shows some pharmacological activity. It is sold as a nutritional supplement because of its analgesic and antidepressant activities. This analgesic activity can be explained by the possible blockage by D-phenylalanine of enkephalin and degradation by the enzyme carboxypeptidase A , and the mechanism of antidepressant activity may be accounted for by the precursor role of L-phenylalanine in the synthesis of the neurotransmitters, norepinephrine and dopamine. High levels of norepinephrine and dopamine are believed to have an anti-depressant effect.

Evodiamine, a bioactive alkaloid extract from the Evodiae Fructus plant, sometimes called Wu-Chu-Yu. Evodiamine is related to capsaicin, found in cayenne pepper. Evodiamine is a vanilloid receptor agonist, and may enhance lipolytic activity. Evodiamine has been shown to raise the body’s skin temperature and decrease core temperature, which is thought to burn calories and fat for energy.

Guarana Extract is the extract of the guarana plant. It contains a significant amount of guaranine, a substance that is similar to caffeine found in coffee beans. It helps stimulate the adrenal glands and increase the production and release of hormones such as epinephrine, norepinephrine (adrenaline), and dopamine. This helps the metabolism of the body that enhances fat loss, and increases energy and endurance. It helps the body burn the fats to be used for energy. It aids in fighting stress, weakness and fatigue. As a stimulant, it also improves mental alertness, clarity, focus, concentration, and memory retention. Guarana also also improves the libido or sex drive in both men and women. Guarana also contains tannins that help prevent diarrhea and soothes the digestive system.

Yerba Matte is potent and refers to a drink that is brewed with dried leaves. It belongs to the holly family that is an evergreen member. This grows in Peru, Argentina, Brazil and Chile. This is as well found in plenty in Paraguay. The Yerba Mate plant is considered as stimulant, aromatic, astringent, bitter, purgative, diuretic and good for inducing sweat and reducing fever. Yerba mate contains many minerals and vitamins. The Yerba Mate leaf has nutrition and antioxidants in plenty and hence North Americans prepare strong tea using this leaf. Yerba mate powder is used to boost immunity and to detoxify blood, restore hair color, combat fatigue, tone nervous system, stimulate mind, control appetite, retard aging, reduce stress and as well eliminate insomnia. The tea is preferred with sugar or some people add mint and few replace the water with milk. The extraction can be done repetitively so that the properties stay beneficial.

Yohimbe, which when ingested, the body converts to yohimbine and assimilates it into the bloodstream. Yohimbe comes from the bark of a tree that grows primarily in Africa. Yohimbine, an alkaloid, is the primary active ingredient of yohimbe. Yohimbe is commonly used as an aphrodisiac and antioxidant. Yohimbe is also used as a vasodilator, which means that it increases blood flow to the extremities and appendages, this is one of the main reasons why it is found in many sexual aids.